O2 for Personalized Medicine and Nutrition:

from inspiration to aspiration

January (28,) 29 and 30, 2015, Amsterdam

VU University Amsterdam, beta building, room WN-C648

(Participant number stands at 27; speakers excluded)


Wednesday 28 January 2015 (Room M212)

14h00-17h00      Hans Westerhoff: pre-course; discussion of introductory material


Thursday 29 January 2015 (Room WN-C648; Beta building; W&N gebouw; VU campus; De Boelelaan 1085; sixth floor)

09h00-09h10:     Hans Westerhoff: Welcome and logistics

09h10-09h55:     Karen van Eunen (UMCG): From systems biology to systems                                          medicine: monogenetic metabolic disorders as a starting point

09h55-10h40:     Piet Hein van der Graaf (UL): Personalized Systems Pharmacology

09h55-10h40:      coffees

11h05-11h50:     Jaap Seidell (VUA): Sociological networks in personalized medicine

11h50-12h35:      Pernette Verschure (O2#):  Epigenetic clocks as perspective for                                           individualized medicine 

12h35-13h30:     lunch

13h30-14h15:      Hans Aerts (LU): Mapping for Gaucher’s and other Inborn Errors of                                       Metabolism

14h15-14h35:     Jurgen Haanstra (O2) and Jacky Snoep (U Stellenbosch,MCISB, O2):                                Differential network–based drug design and parasite heterogeneity

14h35-15h15:     Jurgen Haanstra and Jacky Snoep: Hands-on design of individualized                                 medicine (in silico practical)

15h15-15h45:     Teas

15h45-16h45:     Jurgen Haanstra and Jacky Snoep: Hands-on design of individualized                                 medicine (in silico practical)

16h45-17h00:     Jurgen Haanstra: Differential network –based drug design and parasite                                 heterogeneity: wrap-up

17h00-17h45:      Ilja Arts (Maastricht University): Systems epidemiology: uncovering                                 population heterogeneity in the omics era

18h00-19h00:     Pizza discussions:  Participants presenting slides each about their                                           research interests

19h00-19h15:     Kathrin Thedieck (UMCG): mTOR and personalized medicine -                               approaches and perspectives

19h15-19h45:     Thierry Mondeel and Hans Westerhoff (O2): Flux balance predictions of                             disease and therapy on the basis of the human metabolic map and SNPs:                             a demonstration

19h45-20h00:     coffees

20h00-21h00:     Brain hurricane about Personalized Medicine: Nature or Nurture;                                            molecules, lifestyle and ambition; Chair: Hans V. Westerhoff 


Friday 30 January 2015 (Room WN-C668)


09h00-09h45:     Matteo Barberis (O2):  The cell cycle perspectives for individualized                                    medicine

09h45-10h30:     Renée van Amerongen (O2):  Stem cells and regenerative medicine

10h30-11h00:     coffees

11h00-11h45:     Ben van Ommen (TNO):  Personalized medicine beyond molecules*

11h45-12h30:     Gaston Remmers (HABITUS /Inspire2Liv): Crushed between generic                                  medical assumptions and an erroneous patient identity: why                                                  personalization of health matters from a patients perspective

12h30-13h15:     lunch

13h15-14h00:     Jacky Snoep (U of Stellenbosch, MCISB, O 2): Malaria and JWS-online*

14h00-14h45:     Marijana Radonjic (CEO of Edgeleap, Utrecht): Network analysis for                                     personalized health and disease

14h45-15h30:     Gerard Muyzer (CISBA, UvA): Microbial Systems Ecology and                                               Personalized Medicine

15h30-16h00:     teas

16h00-16h45:     Lodewyk Wessels (NKI): Individualization of cancer therapies

16h45-17h30:     Jaap Heringa (O2): Integrative bioinformatics for personalized medicine                                 and BioSB*

17h30-18h30:     Discussion buffet: planning for the future


Monday 9 February 2015

24h00:                   Course participants (who so desire): submission of 5-page course report                               to H.V.Westerhoff@UvA.NL with ‘course report’ in subject line

Such a course report should discuss 4 lectures (one out of every morning and afternoon), 2 scientific papers in the context of the evening brain hurricane.  It will be assessed by Barbara Bakker and Hans Westerhoff.  A graded diploma for the equivalent of 1.5 ECTS $ will be emailed back.


For program updates:

For course description:




 #: O2=units of the collaborating two Amsterdam Universities (UvA and VUA) that will move into the O|2 building in the fall of 2015

*: lecture title tentative

#: location in program definitive

$: 1 .5 ECTS taken to be equivalent to 42 working hours;


This is program version 2015-01-21


How to get there:

By air:  Plane to Schiphol airport, then see Rail.

By rail: Take train  to Amsterdam Zuid. From Amsterdam ZuidAfter exiting the train walk on the platform to the far Western end of it, walk down the stairs, cross the road and then take a left along a major road with trams and other traffic.  After some 300 m you will have the VU main building in front of you. The betagebouw (Betabuilding) is behind this main building.  Enter the betagebouw and then take an elevator to the sixth floor and make your way to room WN-C648.

By tram: Tram line no. 5 runs between Amsterdam Central Station and Amstelveen Binnenhof. Alight at the De Boelelaan/VU tram stop on Buitenveldertselaan. VU University Medical Center is just over five minutes? walk from this stop.  Tram 16 or 24Start point Amsterdam CS. Alight at final stop (VU).  On your right you will see the main building of the VUA University.  Behind that building you will find the beta building.   Enter the betagebouw and then take an elevator to the sixth floor and and make your way to room WN-C648..

By metro: Metro line 50 runs between Isolatorweg and Gein, via the Amsterdam Sloterdijk railway station. Exit at the Amsterdam Zuid  stop and change to metro 51.  The no. 51 ‘metro’ runs from Amsterdam Central Station to Amstelveen Poortwachter, via the Amsterdam Amstel railway and Amsterdam Zuid stations. Exit at the De Boelelaan/VU stop on Buitenveldertselaan. Cross the road to the main VU building and behind that you will find the beta building.  Enter the betagebouw and then take an elevator to the sixth floor and make your way to room WN-C648.

By car:  From all directions, access the A10, the Amsterdam Ring road (bypass) south of Amsterdam. Drive along the A10 until you reach junction/exit Buitenveldert / Amstelveen / VUmc. At the end of the exit road, turn left towards the VU University Medical Center.  At the subsequent traffic lights go straight on and then after 100 m turn left onto P1 (see map below).  Alternatively follow the map to P2. P3 is closed these days.

The meeting is in the betabuilding (betagebouw, see map), which you reach by taking the stairs and walkway into the hospital (ziekenhuis on the map) [this is complex], leaving onto the Boelelaan (street and using the map).  Make your way to room WN-C648 on the sixth floor.